Journal of General Virology

Fig. 3. Binding map of proteins to E1A. The locations have been determined on the basis of in vitro studies using deletion and mutational analysis. The abbreviations are explained in Table 1. CR1, CR2 and CR3 are constant regions present in a wide range of adenoviruses. PLDLS and LXCXE etc. are recognition motifs. E2F-1 A.D. homology refers to sequences that can displace E2F-1 from Rb and p300.

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