This is an exceptionally interesting book, providing a wealth of information on the basic concepts of host-pathogen evolution, hypothesized by Haldane over 60 years ago, and illustrated with a multitude of examples. The chapters on malarial parasites are engaging and informative and provide a comprehensive picture of various aspects of the co-evolutionary processes at work. The remaining chapters on other pathogens are likewise comprehensive, but some do suffer for being slightly out of date (the first edition was 2004). Nonetheless, these chapters offer a profusion of information which cannot help but leave the reader marvelling at the impact these pathogens have had on human evolution. The final section explores more evolutionary considerations and again provides thought-provoking examples to illustrate the various ideas and hypotheses. I would fully recommend this book to anybody who has an interest in the evolution of pathogens and/or humans and more generally any interest in infectious disease. I would also suggest that it should be held in the library of any institution offering graduate courses in biology as it will be of particular use to students in the field.