Viral Oncology: Basic Science and Clinical Applications

K. Khalili & K.T. Jeang, Eds

John Wiley & Sons Ltd (2010)

This book describes viruses that have been associated with human cancer and the roles they play in its development. It is a shame, however, that it does not mention XMRV and MCV, two viruses recently implicated in prostate- and a rare form of skin cancer, respectively. One should note that, even if a virus is shown to be necessary for cancer development, evidence indicates that it is insufficient, other chemical and physical factors being required. Viruses make a number of contributions. Many supply growth-deregulating functions while others induce immune-suppression (allowing other viruses to contribute) and some induce chronic tissue damage or inflammation that increases the probability of mutation. The book would benefit from a chapter on prevention, including a description of efforts to develop new generations of HPV vaccines. I would recommend this book to all interested in the role that viruses play in cancer development, students and experienced researchers alike. Unfortunately, its price will restrict its purchase to institutions.

Christopher Ring, Middlesex University

£100.50pp. 475ISBN 978-0-47037-991-2