Viruses are primarily classified by the structure of their genomes. Whilst they can be split into either DNA or RNA, single- or double-stranded, there is great diversity in the means by which their genomes are replicated. The first section of the book describes the replication strategies of, with a couple of exceptions, each of the major viral groups. There is an inevitable focus on the member of each group of which most is known, and sometimes insufficient information is provided on others in the group. The second section focuses on mechanistic details, acknowledging that genome replication is not solely the work of polymerases, but other functions such as helicases and integrases. The third section depicts genome replication functions as targets for antiviral intervention, not only describing the inhibition of nucleic acid replication but also the mediation of lethal mutation for reducing viral fitness. I recommend this title to all those interested in viral replication. Unfortunately, its price is likely to be too high for most individuals, however.